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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sh3pxd2b
SH3 and PX domains 2B
MGI:2442062
84 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Sh3pxd2bGt(GST_1527_E5)Lex/Sh3pxd2bGt(GST_1527_E5)Lex
involves: 129X1/SvJ * C57BL/6 		abnormal basicranium morphology J:158635
abnormal cornea morphology J:158635
abnormal craniofacial morphology J:158635
abnormal heart shape J:158635
abnormal heart ventricle morphology J:158635
abnormal iliac crest morphology J:158635
abnormal ilium wing morphology J:158635
abnormal mitral valve morphology J:158635
abnormal myocardial trabeculae morphology J:158635
abnormal neurocranium morphology J:158635
abnormal sagittal suture morphology J:158635
abnormal tooth morphology J:158635
abnormal xiphoid process morphology J:158635
cornea opacity J:158635
decreased abdominal adipose tissue amount J:158635
decreased body size J:158635
decreased heart rate J:158635
decreased subcutaneous adipose tissue amount J:158635
increased cornea size J:158635
increased cornea thickness J:158635
kyphosis J:158635
lordosis J:158635
micrognathia J:158635
mitral valve prolapse J:158635
ocular hypertelorism J:158635
ocular hypertension J:158635
phthisis bulbi J:158635
postnatal growth retardation J:158635
postnatal lethality J:158635
short mandible J:158635
short maxilla J:158635
short nasal bone J:158635
thin interventricular septum J:158635
Wormian bones J:158635
Sh3pxd2bnee/Sh3pxd2bnee
B10.Cg-H2h4 Sh3pxd2bnee/GrsrJ 		abnormal aqueous humor J:262132
abnormal eye anterior chamber morphology J:262132
abnormal iridocorneal angle J:262132
abnormal middle ear morphology J:153369
abnormal postnatal growth J:153369
abnormal retina morphology J:262132
abnormal retina nerve fiber layer morphology J:262132
abnormal skeleton development J:153369
absent Schlemm's canal J:262132
absent trabecular meshwork J:262132
anterior iris synechia J:153369, J:262132
cataract J:262132
cornea opacity J:153369, J:262132
cornea vascularization J:262132
decreased body size J:153369, J:262132
decreased body weight J:153369
decreased bone mineral density J:153369
decreased cornea thickness J:262132
decreased cranium height J:153369
decreased total retina thickness J:262132
decreased white adipose tissue amount J:153369
domed cranium J:153369
enlarged eye anterior chamber J:153369, J:262132
exophthalmos J:153369
eye inflammation J:262132
female infertility J:153369
gliosis J:262132
hyphema J:262132
hypopyon J:262132
increased eye anterior chamber depth J:153369, J:262132
increased or absent threshold for auditory brainstem response J:153369
increased susceptibility to otitis media J:153369
infertility J:153369
irregularly shaped pupil J:262132
male infertility J:153369
mature cataract J:262132
ocular hypertension J:262132
optic nerve atrophy J:262132
optic nerve cupping J:262132
optic nerve degeneration J:262132
posterior subcapsular cataract J:262132
proportional dwarf J:153369
retina ganglion cell degeneration J:262132
short snout J:153369
Sh3pxd2btm1.1Arte/Sh3pxd2btm1.1Arte
involves: C57BL/6NTac 		abnormal adipose tissue development J:235640
abnormal craniofacial morphology J:235640
abnormal skeleton development J:235640
decreased body fat mass J:235640
decreased body size J:235640
decreased body weight J:235640
decreased gonadal fat pad weight J:235640
decreased length of long bones J:235640
decreased renal fat pad weight J:235640
decreased subcutaneous adipose tissue amount J:235640
exophthalmos J:235640
infertility J:235640
kyphosis J:235640
large anterior fontanelle J:235640
lipodystrophy J:235640
short femur J:235640
short tibia J:235640
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory