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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Flcn
folliculin
MGI:2442184
32 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
FlcnGt(RRX115)Byg/Flcn+
involves: 129P2/OlaHsd * C57BL/6 		increased incidence of tumors by chemical induction J:147582
increased kidney tumor incidence J:147582
increased lymphoma incidence J:147582
kidney cyst J:147582
FlcnGt(RRX115)Byg/FlcnGt(RRX115)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal egg cylinder morphology J:173708
abnormal endoderm development J:173708
embryonic lethality between implantation and somite formation, complete penetrance J:173708
prenatal lethality, complete penetrance J:147582
Flcntm1.1Btt/Flcntm1.1Btt
involves: 129S4/SvJaeSor * C57BL/6 		embryonic lethality, complete penetrance J:143922
Flcntm1.1Lss/Flcntm1.1Lss
involves: C57BL/6 * FVB/N * SJL 		prenatal lethality, complete penetrance J:130978
Flcntm1Baba/Flcntm1.1Lss
Tg(CAG-cre/Esr1*)1Lbe/0
involves: 129S1/Sv * 129X1/SvJ 		arrested B cell differentiation J:189078
decreased B cell number J:189078
kidney cyst J:189078
kidney failure J:189078
Flcntm1Baba/Flcntm1.1Lss
Tg(Cdh16-cre)91Igr/0
involves: C57BL/6 * FVB/N * ICR * SJL 		abnormal kidney collecting duct morphology J:130978
abnormal kidney corticomedullary boundary morphology J:130978
abnormal kidney pyramid morphology J:130978
abnormal kidney vasculature morphology J:130978
abnormal renal tubule morphology J:130978
dilated kidney collecting duct J:130978
dilated renal tubule J:130978
distended abdomen J:130978
enlarged kidney J:130978
increased blood urea nitrogen level J:130978
increased kidney cell proliferation J:130978
increased kidney weight J:130978
kidney cyst J:130978
kidney failure J:130978
postnatal lethality, complete penetrance J:130978
premature death J:130978
Flcntm1Btt/Flcntm1Btt
Tg(Cdh16-cre)91Igr/0
involves: 129S4/SvJaeSor * C57BL/6 * ICR 		abnormal renal tubule epithelium morphology J:143922
dilated kidney collecting duct J:143922
dilated proximal convoluted tubule J:143922
increased blood urea nitrogen level J:143922
increased kidney weight J:143922
increased renal carcinoma incidence J:143922
kidney failure J:143922
kidney hemorrhage J:143922
polycystic kidney J:143922
postnatal lethality, complete penetrance J:143922
renal glomerulus atrophy J:143922
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory