Plekha1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Plekha1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
MGI:2442213

16 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)	abnormal spermatocyte morphology	J:142042
	abnormal spermatogenesis	J:142042
	abnormal testis cord formation	J:142042
	abnormal testis morphology	J:142042
	abnormal vascular smooth muscle morphology	J:142042
	decreased circulating testosterone level	J:142042
	decreased Leydig cell number	J:142042
	male infertility	J:142042
	small testis	J:142042
Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} involves: 129S4/SvJaeSor	increased body weight	J:117491
	postnatal lethality	J:117491
Plekha1^tm1.1Arte/Plekha1^tm1.1Arte C57BL/6J-Plekha1^tm1.1Arte	no abnormal phenotype detected	J:169475
Plekha1^{tm1b(EUCOMM)Hmgu}/Plekha1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Plekha1^{tm1b(EUCOMM)Hmgu}/Ieg	abnormal eye morphology	J:211773
	improved glucose tolerance	J:211773
	increased circulating unsaturated transferrin level	J:211773
	increased mean corpuscular volume	J:211773
	small testis	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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