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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gimap5
GTPase, IMAP family member 5
MGI:2442232
71 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gimap5m1Btlr/Gimap5m1Btlr
either: (involves: BALB/cJ * C57BL/6J) or (involves: C3H/HeN * C57BL/6J) or (C57BL/6J * DBA/2J) or (involves: C57BL/6J * FVB/NJ) or (involves: C57BL/6J * NOD/ShiLtJ) 		abnormal liver morphology J:160090
extramedullary hematopoiesis J:160090
Gimap5m1Btlr/Gimap5m1Btlr
involves: C57BL/6J 		abnormal B cell physiology J:160090
abnormal B cell proliferation J:160090
abnormal bone marrow cell morphology/development J:160090
abnormal colon goblet cell morphology J:160090
abnormal common lymphocyte progenitor cell morphology J:160090
abnormal common myeloid progenitor cell morphology J:160090
abnormal intestinal epithelium morphology J:160090
abnormal large intestine crypts of Lieberkuhn morphology J:160090
abnormal liver morphology J:160090
abnormal NK T cell physiology J:160090
abnormal response to transplant J:160090
abnormal spleen B cell follicle morphology J:160090
anemia J:160090
cachexia J:160090
colitis J:160090
decreased B cell number J:160090
decreased B cell proliferation J:160090
decreased B-1 B cell number J:160090
decreased CD8-positive, alpha-beta T cell number J:160090
decreased circulating interferon-gamma level J:160090
decreased circulating interleukin-4 level J:160090
decreased hemoglobin content J:160090
decreased IgG1 level J:160090
decreased IgG2a level J:160090
decreased IgG2b level J:160090
decreased IgG3 level J:160090
decreased IgG level J:160090
decreased IgM level J:160090
decreased interferon-gamma secretion J:160090
decreased interleukin-4 secretion J:160090
decreased lymphocyte cell number J:160090
decreased mature B cell number J:160090
decreased NK cell number J:160090
decreased NK T cell number J:160090
decreased spleen B cell follicle number J:160090
decreased spleen B cell follicle size J:160090
decreased tumor necrosis factor secretion J:160090
diarrhea J:160090
extramedullary hematopoiesis J:160090
increased granulocyte number J:160090
increased hematopoietic stem cell number J:160090
increased neutrophil cell number J:160090
increased red blood cell distribution width J:160090
intestinal inflammation J:160090
normal liver/biliary system phenotype J:160090
postnatal growth retardation J:160090
premature death J:160090
thrombocytopenia J:160090
thymus atrophy J:160090
Gimap5tm1Wlr/Gimap5tm1Wlr
either: B6.129-Gimap5tm1Wlr or C.129-Gimap5tm1Wlr 		abnormal CD8-positive, alpha-beta T cell differentiation J:143620
abnormal erythrocyte cell number J:143620
abnormal erythrocyte morphology J:143620
abnormal erythropoiesis J:143620
abnormal hemoglobin content J:143620
abnormal leukocyte morphology J:143620
abnormal liver development J:143620
abnormal liver parenchyma morphology J:143620
abnormal lymphocyte cell number J:143620
abnormal response to transplant J:143620
abnormal spleen morphology J:143620
anisocytosis J:143620
decreased B cell number J:143620
decreased CD4-positive, alpha-beta T cell number J:143620
decreased CD8-positive, alpha-beta T cell number J:143620
decreased hematocrit J:143620
decreased NK cell number J:143620
decreased NK T cell number J:143620
decreased survivor rate J:143620
decreased T cell number J:143620
hepatic necrosis J:143620
increased granulocyte number J:143620
liver degeneration J:143620
normal liver/biliary system phenotype J:143620
pale liver J:143620
premature death J:143620
small lymph nodes J:143620
spleen hypoplasia J:143620
thrombocytopenia J:143620
Gimap5tm1Yout/Gimap5tm1Yout
involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj 		decreased T cell number J:209926
normal endocrine/exocrine gland phenotype J:209926
normal hematopoietic system phenotype J:209926
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory