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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Thoc2
THO complex 2
MGI:2442413
38 phenotypes from 1 allele in 1 genetic background
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Allelic Composition
Genetic Background		 Annotated Term Reference
Thoc2em1Gecz/Y
C57BL/6JArc-Thoc2em1Gecz 		abnormal axon morphology J:345229
abnormal dendritic spine morphology J:345229
abnormal intracellular organelle physiology J:345229
abnormal mitosis J:345229
abnormal motor capabilities/coordination/movement J:345229
abnormal nervous system electrophysiology J:345229
abnormal nervous system physiology J:345229
abnormal neuron morphology J:345229
abnormal neuronal migration J:345229
abnormal neuronal stem cell self-renewal J:345229
abnormal synapse morphology J:345229
decreased anxiety-related response J:345229
decreased body size J:345229
decreased body weight J:345229
decreased brain size J:345229
decreased brain weight J:345229
decreased corpus callosum size J:345229
decreased cortical ventricular zone thickness J:345229
decreased fetal weight J:345229
decreased heart weight J:345229
decreased kidney weight J:345229
decreased liver weight J:345229
decreased lung weight J:345229
embryonic lethality before implantation, incomplete penetrance J:345229
flattened snout J:345229
impaired coordination J:345229
impaired spatial learning J:345229
impaired spatial working memory J:345229
increased apoptosis J:345229
increased locomotor activity J:345229
premature neuronal precursor differentiation J:345229
short snout J:345229
short stride length J:345229
small heart J:345229
small kidney J:345229
small liver J:345229
small lung J:345229
thin cortical plate J:345229
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory