Rfx7 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rfx7
regulatory factor X, 7
MGI:2442675

10 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rfx7^tm1.1Ggaur/Rfx7^tm1.1Ggaur Commd10^{Tg(Vav1-icre)A2Kio}/Commd10⁺ involves: C57BL/6 * C57BL/10 * CBA/Ca	abnormal NK cell morphology	J:282535
	decreased NK cell number	J:282535
	small spleen	J:282535
Rfx7^tm1.1Ggaur/Rfx7^tm1.1Ggaur Ncr1^{tm1.1(icre)Viv}/Ncr1⁺ involves: C57BL/6	abnormal NK cell physiology	J:282535
	decreased NK cell number	J:282535
	increased susceptibility to viral infection	J:282535
Rfx7^tm1.2Ggaur/Rfx7^tm1.2Ggaur involves: BALB/cJ * C57BL/6	preweaning lethality, incomplete penetrance	J:282535
Rfx7^{tm2b(EUCOMM)Hmgu}/Rfx7⁺ C57BL/6N-Rfx7^{tm2b(EUCOMM)Hmgu}/H	abnormal retina morphology	J:211773
	decreased fasting circulating glucose level	J:211773
	decreased locomotor activity	J:211773
	decreased thigmotaxis	J:211773
Rfx7^{tm2b(EUCOMM)Hmgu}/Rfx7^{tm2b(EUCOMM)Hmgu} C57BL/6N-Rfx7^{tm2b(EUCOMM)Hmgu}/H	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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