Tigar Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tigar
Trp53 induced glycolysis regulatory phosphatase
MGI:2442752

8 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tigar^{Gt(EUCE0047g05)Hmgu}/Tigar^{Gt(EUCE0047g05)Hmgu} involves: 129P2/OlaHsd	abnormal small intestinal crypt cell physiology	J:198650
	abnormal small intestinal crypt cell proliferation	J:198650
	increased cellular sensitivity to alkylating agents	J:198650
	increased cellular sensitivity to gamma-irradiation	J:198650
	increased small intestinal crypt cell apoptosis	J:198650
	increased susceptibility to induced colitis	J:198650
	increased susceptibility to xenobiotic induced morbidity/mortality	J:198650
	oxidative stress	J:198650
Tigar^tm1.1Khv/Tigar^tm1.1Khv Tg(CMV-cre)1Cgn/0 involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * SJL	increased susceptibility to induced colitis	J:198650

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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