Tigar Phenotype Annotations - Multigenic Genotypes

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tigar
Trp53 induced glycolysis regulatory phosphatase
MGI:2442752

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Tigar^{Gt(EUCE0047g05)Hmgu}/Tigar^{Gt(EUCE0047g05)Hmgu} Apc^tm1Tno/Apc^tm1Tno Lgr5^{tm1(cre/ERT2)Cle}/Lgr5⁺ involves: 129P2/OlaHsd * 129S4/SvJae	decreased susceptibility to induced morbidity/mortality	J:198650
	decreased tumor growth/size	J:198650
Tigar^tm1.2Smat/Tigar^tm1.2Smat Tg(CAG-EGFP/Map1lc3b)53Nmz/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6JJcl * C57BL/6NCrj	abnormal autophagy	J:183674
	abnormal heart morphology	J:183674
	abnormal mitochondrial chromosome morphology	J:183674
	abnormal mitochondrial physiology	J:183674
	abnormal response to cardiac infarction	J:183674
	decreased cardiomyocyte apoptosis	J:183674
	increased cardiac muscle contractility	J:183674
	oxidative stress	J:183674

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 08/21/2024 MGI 6.24