Tigar Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tigar
Trp53 induced glycolysis regulatory phosphatase
MGI:2442752

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Tigar^{Gt(EUCE0047g05)Hmgu}/Tigar^{Gt(EUCE0047g05)Hmgu} Apc^tm1Tno/Apc^tm1Tno Lgr5^{tm1(cre/ERT2)Cle}/Lgr5⁺ involves: 129P2/OlaHsd * 129S4/SvJae	decreased susceptibility to induced morbidity/mortality	J:198650
	decreased tumor growth/size	J:198650
Tigar^tm1.2Smat/Tigar^tm1.2Smat Tg(CAG-EGFP/Map1lc3b)53Nmz/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6JJcl * C57BL/6NCrj	abnormal autophagy	J:183674
	abnormal heart morphology	J:183674
	abnormal mitochondrial chromosome morphology	J:183674
	abnormal mitochondrial physiology	J:183674
	abnormal response to cardiac infarction	J:183674
	decreased cardiomyocyte apoptosis	J:183674
	increased cardiac muscle contractility	J:183674
	oxidative stress	J:183674

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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