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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Paxx
non-homologous end joining factor
MGI:2442831
16 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Paxxem1(IMPC)Mbp/Paxxem1(IMPC)Mbp
C57BL/6NCrl-Paxxem1(IMPC)Mbp/Mmucd 		abnormal lymph node morphology J:211773
abnormal uterus morphology J:211773
enlarged lymph nodes J:211773
increased freezing behavior J:211773
Paxxem1Spj/Paxxem1Spj
C57BL/6NTac-Paxxem1Spj 		normal cellular phenotype J:236776
decreased B cell number J:236776
decreased CD4-positive, alpha-beta T cell number J:236776
decreased CD8-positive, alpha-beta T cell number J:236776
decreased follicular B cell number J:236776
decreased splenocyte number J:236776
decreased T cell number J:236776
decreased transitional stage B cell number J:236776
normal immune system phenotype J:236776
increased mature B cell number J:236776
increased mortality induced by gamma-irradiation J:236776
normal neoplasm J:236776
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory