Paxx Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Paxx
non-homologous end joining factor
MGI:2442831

21 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Atm^tm1Awb/Atm^tm1Awb Paxx^em1Spj/Paxx^em1Spj involves: A/J * C57BL/6NTac	abnormal class switch recombination	J:236776
	decreased B cell number	J:236776
	decreased splenocyte number	J:236776
	decreased T cell number	J:236776
	normal mortality/aging	J:236776
Paxx^em1Spj/Paxx^em1Spj Lig4^tm1Fwa/Lig4^tm1Fwa involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac	prenatal lethality, complete penetrance	J:236776
Paxx^em1Spj/Paxx^em1Spj Nhej1^tm1Fwa/Nhej1^tm1Fwa involves: 129S6/SvEvTac * C57BL/6NTac	abnormal thymus involution	J:236776
	absent lymphocyte	J:236776
	athymia	J:236776
	chromosomal instability	J:236776
	decreased birth body size	J:236776
	decreased body size	J:236776
	decreased body weight	J:236776
	decreased embryo size	J:236776
	decreased fetal size	J:236776
	decreased fetal weight	J:236776
	decreased spleen weight	J:236776
	decreased splenocyte number	J:236776
	increased neural tube apoptosis	J:236776
	lethality throughout fetal growth and development, incomplete penetrance	J:236776
	postnatal lethality, incomplete penetrance	J:236776
	small spleen	J:236776
Paxx^em1Spj/Paxx^em1Spj Xrcc5^tm1Nus/Xrcc5^tm1Nus involves: C57BL/6 * C57BL/6NTac	postnatal lethality, incomplete penetrance	J:236776

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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