Rigi Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rigi
RNA sensor RIG-I
MGI:2442858

29 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rigi^em1(IMPC)J/Rigi^em1(IMPC)J C57BL/6NJ-Rigi^em1(IMPC)J/Mmjax	abnormal coat/hair pigmentation	J:211773
	abnormal vocalization	J:211773
Rigi^em1(IMPC)Mbp/Rigi^em1(IMPC)Mbp C57BL/6N-Rigi^em1(IMPC)Mbp/MbpMmucd	abnormal liver morphology	J:211773
	impaired glucose tolerance	J:211773
	small liver	J:211773
Rigi^tm1Aki/Rigi^tm1Aki involves: 129/Sv * C57BL/6	abnormal cell physiology	J:137522
Rigi^tm1Aki/Rigi^tm1Aki involves: 129/Sv * C57BL/6	abnormal dendritic cell physiology	J:137522
Rigi^tm1Aki/Rigi^tm1Aki involves: 129/Sv * C57BL/6 * ICR	abnormal interferon level	J:137522
	decreased survivor rate	J:137522
	increased susceptibility to Flaviviridae infection induced morbidity/mortality	J:137522
Rigi^tm1Aki/Rigi^tm1Aki Not Specified	embryonic lethality during organogenesis, incomplete penetrance	J:100539
	liver degeneration	J:100539
	postnatal lethality, complete penetrance	J:100539
Rigi^tm1Zgwg/Rigi^tm1Zgwg involves: 129S1/Sv	abnormal B cell differentiation	J:139016
	abnormal granulocyte morphology	J:139016
	abnormal granulocyte physiology	J:139016
	colitis	J:139868
	decreased Peyer's patch number	J:139868
	decreased T cell number	J:139868
	enlarged spleen	J:139016
	extramedullary hematopoiesis	J:139016
	normal immune system phenotype	J:139016
	increased activated T cell number	J:139868
	increased chronic myelocytic leukemia incidence	J:139016
	increased granulocyte number	J:139016
	increased memory T cell number	J:139868
	increased susceptibility to induced colitis	J:139868
	small Peyer's patches	J:139868
	weight loss	J:139868

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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