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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Zfp574
zinc finger protein 574
MGI:2442951
32 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Zfp574em1Btlr/Zfp574em1Btlr
C57BL/6J-Zfp574em1Btlr 		abnormal B cell physiology J:354285
abnormal class switch recombination J:354285
abnormal humoral immune response J:354285
decreased B cell number J:354285
decreased B cell proliferation J:354285
decreased B-1 B cell number J:354285
decreased erythrocyte cell number J:354285
decreased hematocrit J:354285
decreased hemoglobin content J:354285
decreased IgA level J:354285
decreased IgG1 level J:354285
decreased IgG2a level J:354285
decreased IgG2b level J:354285
decreased IgG level J:354285
decreased IgM level J:354285
decreased immunoglobulin level J:354285
decreased leukocyte cell number J:354285
decreased lymphocyte cell number J:354285
decreased mean corpuscular hemoglobin concentration J:354285
decreased monocyte cell number J:354285
decreased neutrophil cell number J:354285
decreased T cell number J:354285
increased B cell apoptosis J:354285
increased mean corpuscular hemoglobin J:354285
increased mean corpuscular volume J:354285
increased red blood cell distribution width J:354285
macrocytic anemia J:354285
pancytopenia J:354285
thrombocytopenia J:354285
Zfp574em1Btlr/Zfp574em2Btlr
C57BL/6J-Zfp574em1Btlr Zfp574em2Btlr 		prenatal lethality, complete penetrance J:354285
Zfp574em2Btlr/Zfp574em2Btlr
C57BL/6J-Zfp574em2Btlr 		prenatal lethality, complete penetrance J:354285
Zfp574em3Btlr/Zfp574em3Btlr
Ndor1Tg(UBC-cre/ERT2)1Ejb/Ndor1+
B6.Cg-Ndor1Tg(UBC-cre/ERT2)1Ejb Zfp574em3Btlr 		abnormal hematopoietic stem cell morphology J:354285
decreased B cell number J:354285
macrocytic anemia J:354285
pancytopenia J:354285
Zfp574m1Btlr/Zfp574m1Btlr
C57BL/6J-Zfp574m1Btlr 		abnormal humoral immune response J:354285
abnormal T cell physiology J:354285
decreased B cell number J:354285
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory