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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pcid2
PCI domain containing 2
MGI:2443003
30 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cul4a/Pcid2tm2Ktc/Cul4a/Pcid2tm2Ktc
Tg(Mx1-cre)1Cgn/0
involves: 129S/SvEv * C57BL/6 * CBA * FVB/N 		abnormal definitive hematopoiesis J:138468
abnormal enterocyte morphology J:138468
abnormal leukocyte morphology J:138468
abnormal small intestine crypts of Lieberkuhn morphology J:138468
abnormal spleen capsule morphology J:138468
abnormal spleen morphology J:138468
decreased bone marrow cell number J:138468
decreased hematocrit J:138468
decreased hematopoietic stem cell number J:138468
decreased lymphocyte cell number J:138468
decreased monocyte cell number J:138468
decreased neutrophil cell number J:138468
decreased spleen red pulp amount J:138468
decreased spleen weight J:138468
decreased spleen white pulp amount J:138468
impaired hematopoiesis J:138468
increased enterocyte apoptosis J:138468
premature death J:138468
small intestinal villus atrophy J:138468
small thymus J:138468
spleen hypoplasia J:138468
thrombocytopenia J:138468
Pcid2em1(IMPC)Ccpcz/Pcid2+
C57BL/6NCrl-Pcid2em1(IMPC)Ccpcz/Ccpcz 		abnormal eye morphology J:211773
increased hemoglobin content J:211773
Pcid2em1(IMPC)Ccpcz/Pcid2em1(IMPC)Ccpcz
C57BL/6NCrl-Pcid2em1(IMPC)Ccpcz/Ccpcz 		preweaning lethality, complete penetrance J:211773
Pcid2tm1.1Imku/Pcid2tm1.1Imku
involves: C57BL/6NCrlj * CBA/JNCrlj 		embryonic lethality before implantation, complete penetrance J:283440
Pcid2tm1Imku/Pcid2tm1Imku
Cd19tm1(cre)Cgn/Cd19+
involves: 129P2/OlaHsd * C57BL/6 * CBA 		abnormal spleen B cell follicle morphology J:166080
decreased follicular B cell number J:166080
decreased marginal zone B cell number J:166080
decreased mature B cell number J:166080
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory