Pcid2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pcid2
PCI domain containing 2
MGI:2443003

27 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cul4a/Pcid2^tm2Ktc/Cul4a/Pcid2^tm2Ktc Tg(Mx1-cre)1Cgn/0 involves: 129S/SvEv * C57BL/6 * CBA * FVB/N	abnormal definitive hematopoiesis	J:138468
	abnormal enterocyte morphology	J:138468
	abnormal leukocyte morphology	J:138468
	abnormal small intestine crypts of Lieberkuhn morphology	J:138468
	abnormal spleen capsule morphology	J:138468
	abnormal spleen morphology	J:138468
	decreased bone marrow cell number	J:138468
	decreased hematocrit	J:138468
	decreased hematopoietic stem cell number	J:138468
	decreased lymphocyte cell number	J:138468
	decreased monocyte cell number	J:138468
	decreased neutrophil cell number	J:138468
	decreased spleen red pulp amount	J:138468
	decreased spleen weight	J:138468
	decreased spleen white pulp amount	J:138468
	impaired hematopoiesis	J:138468
	increased enterocyte apoptosis	J:138468
	premature death	J:138468
	small intestinal villus atrophy	J:138468
	small thymus	J:138468
	spleen hypoplasia	J:138468
	thrombocytopenia	J:138468
Pcid2^tm1.1Imku/Pcid2^tm1.1Imku involves: C57BL/6NCrlj * CBA/JNCrlj	embryonic lethality before implantation, complete penetrance	J:283440
Pcid2^tm1Imku/Pcid2^tm1Imku Cd19^tm1(cre)Cgn/Cd19⁺ involves: 129P2/OlaHsd * C57BL/6 * CBA	abnormal spleen B cell follicle morphology	J:166080
	decreased follicular B cell number	J:166080
	decreased marginal zone B cell number	J:166080
	decreased mature B cell number	J:166080

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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