Mib1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mib1
MIB E3 ubiquitin protein ligase 1
MGI:2443157

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apcdd1^em1Jlp/Apcdd1⁺ Asxl3^em1Jlp/Asxl3⁺ Mib1^em1Jlp/Mib1⁺ C57BL/6-Apcdd1^em1Jlp Asxl3^em1Jlp Mib1^em1Jlp	dilated heart	J:338889
	increased cardiac output	J:338889
	increased heart left ventricle weight	J:338889
	thin ventricle myocardium compact layer	J:338889
Bcl7a^em1Jlp/Bcl7a⁺ Cep192^em1Jlp/Cep192⁺ Mib1^em2Jlp/Mib1⁺ Tmx3^em1Jlp/Tmx3⁺ C57BL/6-Bcl7a^em1Jlp Cep192^em1Jlp Mib1^em2Jlp Tmx3^em1Jlp	abnormal coronary artery morphology	J:338889
	abnormal interventricular septum membranous part morphology	J:338889
	abnormal interventricular septum muscular part morphology	J:338889
	bicuspid aortic valve	J:338889
Cep192^em1Jlp/Cep192⁺ Mib1^em2Jlp/Mib1⁺ Tmx3^em1Jlp/Tmx3⁺ C57BL/6-Cep192^em1Jlp Mib1^em2Jlp Tmx3^em1Jlp	abnormal coronary artery morphology	J:338889
	abnormal interventricular septum membranous part morphology	J:338889
	abnormal interventricular septum muscular part morphology	J:338889
	bicuspid aortic valve	J:338889
Mib1^em1Jlp/Mib1⁺ Notch1^tm1Con/Notch1⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	normal cardiovascular system phenotype	J:338889
Mib1^em2Jlp/Mib1⁺ Notch1^tm1Con/Notch1⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal aortic valve morphology	J:338889
	bicuspid aortic valve	J:338889
	normal cardiovascular system phenotype	J:338889
Mib1^tm1Kong/Mib1⁺ Mib2^tm1Kong/Mib2^tm1Kong involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:130369
Mib1^tm1Kong/Mib1^tm1Kong Mib2^tm1Kong/Mib2⁺ involves: 129P2/OlaHsd * C57BL/6	embryonic lethality	J:130369
Mib1^tm1Kong/Mib1^tm1Kong Mib2^tm1Kong/Mib2^tm1Kong involves: 129P2/OlaHsd * C57BL/6	embryonic lethality	J:130369

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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