Orai2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Orai2
ORAI calcium release-activated calcium modulator 2
MGI:2443195

6 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Orai2^{tm1.1(KOMP)Vlcg}/Orai2^{tm1.1(KOMP)Vlcg} B6.Cg-Orai2^{tm1.1(KOMP)Vlcg}	abnormal macrophage physiology	J:241365
	abnormal T cell physiology	J:241365
Orai2^tm1.1Itl/Orai2^tm1.1Itl Tg(Cma1-cre)#Roer/0 involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N	increased susceptibility to type I hypersensitivity reaction	J:278536
Orai2^tm1.2Itl/Orai2^tm1.2Itl involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6 * C57BL/6N	abnormal mast cell physiology	J:278536
	increased mast cell degranulation	J:278536
	normal mortality/aging	J:278536

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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