Orai2 Phenotype Annotations - Multigenic Genotypes

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Orai2
ORAI calcium release-activated calcium modulator 2
MGI:2443195

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Orai1^tm1.1Hjm/Orai1^tm1.1Hjm Orai2^{tm1.1(KOMP)Vlcg}/Orai2^{tm1.1(KOMP)Vlcg} Tg(Cd4-cre)1Cwi/0 B6.Cg-Tg(Cd4-cre)1Cwi Orai1^tm1.1Hjm Orai2^{tm1.1(KOMP)Vlcg}	abnormal CD4-positive helper T cell morphology	J:241365
	abnormal T cell physiology	J:241365
	decreased germinal center B cell number	J:241365
	decreased IgG level	J:241365
	decreased regulatory T cell number	J:241365
	decreased single-positive T cell number	J:241365
	normal hematopoietic system phenotype	J:241365
	normal immune system phenotype	J:241365
	lymph node hyperplasia	J:241365
	spleen hyperplasia	J:241365

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24