Rbm15 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rbm15
RNA binding motif protein 15
MGI:2443205

16 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rbm15^{tm1.1(MAL)Dgg}/Rbm15^{tm1.1(MAL)Dgg} B6.129-Rbm15^{tm1.1(MAL)Dgg}	abnormal common myeloid progenitor cell morphology	J:149622
	extramedullary hematopoiesis	J:149622
	increased hematopoietic stem cell number	J:149622
	increased leukemia incidence	J:149622
Rbm15^tm1.1Dgg/Rbm15^tm1.1Dgg involves: 129S1/Sv * 129X1/SvJ * FVB/N	embryonic lethality during organogenesis, complete penetrance	J:120321
Rbm15^tm1Dgg/Rbm15^tm1.1Dgg Tg(Mx1-cre)1Cgn/0 involves: 129/Sv * C57BL/6 * CBA * FVB/N	abnormal B cell differentiation	J:120321
	decreased B cell number	J:120321
	decreased pre-B cell number	J:120321
	increased hematopoietic stem cell number	J:120321
	increased megakaryocyte cell number	J:120321
	increased spleen red pulp amount	J:120321
Rbm15^tm1Swm/Rbm15^tm1Swm Tg(Mx1-cre)1Cgn/0 involves: 129X1/SvJ * C57BL/6 * CBA	abnormal definitive hematopoiesis	J:152262
	abnormal megakaryocyte differentiation	J:152262
	decreased hemoglobin content	J:152262
	decreased leukocyte cell number	J:152262
	decreased lymphocyte cell number	J:152262
	decreased neutrophil cell number	J:152262
	increased hematopoietic stem cell number	J:152262
	increased megakaryocyte cell number	J:152262
	increased spleen red pulp amount	J:152262

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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