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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Slc4a5
solute carrier family 4, sodium bicarbonate cotransporter, member 5
MGI:2443220
31 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Slc4a5tm1.1Boet/Slc4a5tm1.1Boet
involves: 129 * C57BL/6 		abnormal blood homeostasis J:180608
abnormal urine homeostasis J:180608
decreased circulating aldosterone level J:180608
decreased circulating bicarbonate level J:180608
decreased circulating creatinine level J:180608
decreased circulating renin level J:180608
delayed kidney development J:180608
normal endocrine/exocrine gland phenotype J:180608
increased circulating atrial natriuretic factor J:180608
increased renal glomerular filtration rate J:180608
increased systemic arterial diastolic blood pressure J:180608
increased systemic arterial systolic blood pressure J:180608
increased urine bicarbonate level J:180608
increased urine protein level J:180608
normal nervous system phenotype J:180608
polyuria J:180608
renal tubular acidosis J:180608
Slc4a5tvrm77/Slc4a5tvrm77
C57BL/6J-Slc4a5tvrm77/Pjn 		abnormal electroretinogram waveform feature J:321062
abnormal ocular fundus morphology J:321062
abnormal retina morphology J:321062
abnormal retina pigment epithelium morphology J:321062
decreased a-wave amplitude J:321062
decreased b-wave amplitude J:321062
decreased FO-wave amplitude J:321062
increased c-wave amplitude J:321062
retina degeneration J:321062
retina detachment J:321062
retina fold J:321062
retina neovascularization J:321062
retina spots J:321062
thin retina outer nuclear layer J:321062
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory