About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Siglech
sialic acid binding Ig-like lectin H
MGI:2443256
13 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Siglechtm1.1Cln/Siglech+
Tg(CLEC4C-HBEGF)956Cln/0
involves: C57BL/6 		decreased plasmacytoid dendritic cell number J:166504
Siglechtm1.1Ksat/Siglechtm1.1Ksat
B6.Cg-Siglechtm1.1Ksat 		abnormal circulating cytokine level J:179283
abnormal dendritic cell antigen presentation J:179283
abnormal plasmacytoid dendritic cell physiology J:179283
abnormal regulatory T cell morphology J:179283
decreased circulating interferon-alpha level J:179283
decreased circulating interleukin-12b level J:179283
decreased plasmacytoid dendritic cell number J:179283
decreased susceptibility to bacterial infection induced morbidity/mortality J:179283
decreased susceptibility to infection induced morbidity/mortality J:179283
decreased T-helper 17 cell number J:179283
increased circulating interferon-alpha level J:179283
increased circulating interleukin-12b level J:179283
increased T-helper 17 cell number J:179283
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory