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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tnni3k
TNNI3 interacting kinase
MGI:2443276
14 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Tnni3kB/Tnni3kB
involves: C57BL/6J * DBA/2J
decreased cardiac muscle contractility J:339644
decreased circulating insulin level J:339644
decreased heart left ventricle posterior wall thickness J:339644
decreased heart rate J:339644
dilated heart left ventricle J:339644
hyperglycemia J:339644
insulin resistance J:339644
Tnni3ktm1.1Tfo/Tnni3ktm1.1Tfo
involves: C57BL/6
abnormal cell proliferation J:249318
abnormal myocardial fiber physiology J:249318
increased myocardial fiber number J:249318
normal muscle phenotype J:249318
Tnni3ktm1Tfo/Tnni3ktm1Tfo
A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+
involves: C57BL/6 * FVB/N
abnormal myocardial fiber physiology J:213546
abnormal response to cardiac infarction J:213546
normal cardiovascular system phenotype J:213546
decreased myocardial infarct size J:213546
Tnni3ktm1Tfo/Tnni3ktm1Tfo
A1cfTg(Myh6-cre/Esr1*)1Jmk/?
involves: C57BL/6 * FVB/N
increased myocardial fiber number J:249318

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory