Tmc7 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tmc7
transmembrane channel-like gene family 7
MGI:2443317

18 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tmc7^em1(IMPC)Mbp/Tmc7^em1(IMPC)Mbp C57BL/6NCrl-Tmc7^em1(IMPC)Mbp/Mmucd	abnormal eye morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal ovary morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	enlarged spleen	J:211773
	female infertility	J:211773
	increased circulating cholesterol level	J:211773
	male infertility	J:211773
	microphthalmia	J:211773
Tmc7^em1Zjl/Tmc7^em1Zjl C57BL/6J-Tmc7^em1Zjl	abnormal acrosome assembly	J:359286
	abnormal acrosome morphology	J:359286
	abnormal male germ cell physiology	J:359286
	abnormal proacrosomal vesicle fusion	J:359286
	abnormal sperm head morphology	J:359286
	abnormal spermiogenesis	J:359286
	increased male germ cell apoptosis	J:359286
	male infertility	J:359286
	small testis	J:359286

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24