Trib1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trib1
tribbles pseudokinase 1
MGI:2443397

21 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Trib1^tm1Aki/Trib1^tm1Aki involves: 129P2/OlaHsd	abnormal common myeloid progenitor cell morphology	J:196449
	abnormal epididymal fat pad morphology	J:196449
	abnormal spleen red pulp morphology	J:196449
	decreased body weight	J:126085
	decreased eosinophil cell number	J:196449
	decreased interleukin-12 secretion	J:126085
	decreased macrophage cell number	J:196449
	decreased spleen iron level	J:196449
	decreased white fat cell size	J:196449
	impaired glucose tolerance	J:196449
	increased liver iron level	J:196449
	increased neutrophil cell number	J:196449
	insulin resistance	J:196449
	lipodystrophy	J:196449
	postnatal growth retardation	J:126085
Trib1^{tm1b(KOMP)Wtsi}/Trib1⁺ C57BL/6N-Trib1^{tm1b(KOMP)Wtsi}/Bay	abnormal coat appearance	J:211773
	abnormal skin coloration	J:211773
	unresponsive to tactile stimuli	J:211773
Trib1^{tm1b(KOMP)Wtsi}/Trib1^{tm1b(KOMP)Wtsi} C57BL/6N-Trib1^{tm1b(KOMP)Wtsi}/Bay	abnormal coat appearance	J:211773
	abnormal embryo size	J:211773
	decreased bone mineral density	J:211773
	preweaning lethality, incomplete penetrance	J:211773
	unresponsive to tactile stimuli	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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