Tbc1d24 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tbc1d24
TBC1 domain family, member 24
MGI:2443456

16 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tbc1d24^em1Tbf/Tbc1d24^em1Tbf C57BL/6J-Tbc1d24^em1Tbf	perinatal lethality, complete penetrance	J:273646
Tbc1d24^em2Tbf/Tbc1d24^em2Tbf C57BL/6J-Tbc1d24^em2Tbf	normal hearing/vestibular/ear phenotype	J:273646
	normal nervous system phenotype	J:273646
	postnatal lethality, complete penetrance	J:273646
	tonic-clonic seizures	J:273646
Tbc1d24^em2Tbf/Tbc1d24^em5Tbf C57BL/6J-Tbc1d24^em2Tbf Tbc1d24^em5Tbf	normal hearing/vestibular/ear phenotype	J:299025
	postnatal lethality, complete penetrance	J:299025
	seizures	J:299025
Tbc1d24^em3Tbf/Tbc1d24^em3Tbf C57BL/6J-Tbc1d24^em3Tbf	normal hearing/vestibular/ear phenotype	J:299025
Tbc1d24^em4Tbf/Tbc1d24^em4Tbf C57BL/6J-Tbc1d24^em4Tbf	normal hearing/vestibular/ear phenotype	J:299025
Tbc1d24^em5Tbf/Tbc1d24^em5Tbf C57BL/6J-Tbc1d24^em5Tbf	prenatal lethality, complete penetrance	J:299025
Tbc1d24^{tm1b(EUCOMM)Hmgu}/Tbc1d24⁺ B6J.B6N-Tbc1d24^{tm1b(EUCOMM)Hmgu}	abnormal axon extension	J:271632
	abnormal dendrite morphology	J:271632
	abnormal endocytosis	J:271632
	abnormal miniature excitatory postsynaptic currents	J:271632
	abnormal synaptic transmission	J:271632
	abnormal synaptic vesicle recycling	J:271632
	normal behavior/neurological phenotype	J:271632
	normal growth/size/body region phenotype	J:271632
	normal hearing/vestibular/ear phenotype	J:271632
	increased cellular sensitivity to oxidative stress	J:271632
	normal nervous system phenotype	J:271632

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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