About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Slc9a6
solute carrier family 9 (sodium/hydrogen exchanger), member 6
MGI:2443511
31 phenotypes from 2 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Slc9a6tm1Dgen/Y
B6.129P2-Slc9a6tm1Dgen/J 		abnormal amygdala morphology J:229166, J:241124
abnormal brain morphology J:241124
abnormal cerebellar molecular layer J:229166
abnormal cerebellum morphology J:262453
abnormal cerebral hemisphere morphology J:262453
abnormal enzyme/coenzyme activity J:241124
abnormal hippocampus morphology J:262453
abnormal neuron morphology J:241124
abnormal Purkinje cell axon morphology J:241124
abnormal spatial reference memory J:229166
astrocytosis J:262453
ataxia J:229166
normal behavior/neurological phenotype J:241124
decreased brain size J:262453
decreased striatum size J:262453
gliosis J:229166
impaired coordination J:229166, J:241124
increased ganglioside level J:229166, J:241124
increased locomotor activity J:229166, J:241124
increased vertical activity J:241124
microgliosis J:262453
Purkinje cell degeneration J:229166, J:241124, J:262453
small cerebellum J:262453
thin cerebral cortex J:262453
Slc9a6tm1Dgen/Slc9a6+
B6.129P2-Slc9a6tm1Dgen/J 		abnormal amygdala morphology J:229166
abnormal hippocampus CA3 region morphology J:229166
abnormal hippocampus CA4 region morphology J:229166
abnormal spatial reference memory J:229166
decreased Purkinje cell number J:262453
gliosis J:229166
impaired coordination J:229166
increased ganglioside level J:229166
Purkinje cell degeneration J:229166
Slc9a6tm1Dgen/Y
involves: 129P2/OlaHsd * C57BL/6 		increased locomotor activity J:101679
increased susceptibility to pharmacologically induced seizures J:101679
Slc9a6tm1Dgen/Slc9a6tm1Dgen
B6.129P2-Slc9a6tm1Dgen/J 		abnormal amygdala morphology J:241124
abnormal brain cholesterol level J:241124
abnormal brain morphology J:241124
abnormal cerebral cortex morphology J:241124
abnormal enzyme/coenzyme activity J:241124
abnormal neuron morphology J:241124
abnormal Purkinje cell axon morphology J:241124
normal behavior/neurological phenotype J:241124
increased ganglioside level J:241124
postnatal lethality, incomplete penetrance J:241124
Purkinje cell degeneration J:241124
Slc9a6tm1Tigm/Y
B6J.Cg-Slc9a6tm1Tigm 		decreased Purkinje cell number J:262453
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory