Abat Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Abat
4-aminobutyrate aminotransferase
MGI:2443582

8 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Abat^em2(IMPC)Bay/Abat^em2(IMPC)Bay C57BL/6N-Abat^em2(IMPC)Bay/Bay	preweaning lethality, complete penetrance	J:211773
Abat^{tm1c(EUCOMM)Hmgu}/Abat^{tm1c(EUCOMM)Hmgu} Tg(Cd4-cre)1Cwi/0 involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N * DBA/2	abnormal CD4-positive T cell differentiation	J:333883
	abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology	J:333883
	abnormal T-helper 1 cell differentiation	J:333883
	abnormal T-helper 17 cell differentiation	J:333883
	decreased susceptibility to experimental autoimmune encephalomyelitis	J:333883
	decreased T cell proliferation	J:333883
	normal immune system phenotype	J:333883

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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