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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
MGI:2443878
37 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Slc4a7Gt(40G1)Cmhd/Slc4a7Gt(40G1)Cmhd
B6.129-Slc4a7Gt(40G1)Cmhd 		abnormal heart rate J:189470
abnormal systemic arterial blood pressure J:189470
abnormal vascular endothelial cell physiology J:189470
abnormal vascular smooth muscle physiology J:189470
abnormal vasoconstriction J:189470
decreased vasodilation J:189470
increased heart rate J:189470
increased mean systemic arterial blood pressure J:189470
preweaning lethality, incomplete penetrance J:189470
Slc4a7Gt(RRL021)Byg/Slc4a7Gt(RRL021)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal pH regulation J:132199
Slc4a7tm1Krtz/Slc4a7tm1Krtz
involves: 129S5/SvEvBrd * C57BL/6 		abnormal auditory brainstem response waveform shape J:86635
abnormal Claudius cell morphology J:102942
abnormal ocular fundus morphology J:86635
abnormal retina apoptosis J:86635
abnormal retina vasculature morphology J:86635
abnormal rod electrophysiology J:86635
abnormal spiral ligament fibrocyte morphology J:102942
abnormal spiral ligament morphology J:86635
abnormal stria vascularis morphology J:86635
abnormal type I spiral ligament fibrocytes J:102942
blindness J:86635
cochlear degeneration J:86635
cochlear ganglion degeneration J:86635, J:102942
cochlear hair cell degeneration J:86635, J:102942
cochlear inner hair cell degeneration J:86635, J:102942
cochlear outer hair cell degeneration J:86635, J:102942
collapsed Reissner membrane J:86635
decreased retina photoreceptor cell number J:86635
degeneration of organ of Corti supporting cells J:102942
increased or absent threshold for auditory brainstem response J:86635
organ of Corti degeneration J:102942
photoreceptor outer segment degeneration J:86635
retina photoreceptor degeneration J:86635
short photoreceptor outer segment J:86635
thin retina outer nuclear layer J:86635
type II spiral ligament fibrocyte degeneration J:102942
type IV spiral ligament fibrocyte degeneration J:102942
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory