Rasal2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rasal2
RAS protein activator like 2
MGI:2443881

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Rasal2^{Gt(463C12)Cmhd}/Rasal2⁺ Trp53^tm1Tyj/Trp53^tm1Tyj involves: 129S * 129X1/SvJ * C57BL/6 * C57BL/6NCrl	increased metastatic potential	J:202603
Rasal2^{Gt(463C12)Cmhd}/Rasal2^{Gt(463C12)Cmhd} Tg(MMTVneu)202Mul/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl * FVB/N	increased mammary adenocarcinoma incidence	J:202603
	increased metastatic potential	J:202603
Rasal2^{Gt(463C12)Cmhd}/Rasal2^{Gt(463C12)Cmhd} Trp53^tm1Tyj/Trp53^tm1Tyj involves: 129S * 129X1/SvJ * C57BL/6 * C57BL/6NCrl	decreased tumor-free survival time	J:202603
	increased colon adenoma incidence	J:202603
	increased hepatocellular carcinoma incidence	J:202603
	increased liver tumor incidence	J:202603
	increased lymphoma incidence	J:202603
	increased metastatic potential	J:202603
	increased mouth tumor incidence	J:202603
	increased stomach tumor incidence	J:202603

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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