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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cadps2
Ca2+-dependent activator protein for secretion 2
MGI:2443963
39 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cadps2em1(IMPC)Rbrc/Cadps2em1(IMPC)Rbrc
C57BL/6NJcl-Cadps2em1(IMPC)Rbrc/Rbrc 		abnormal circulating alkaline phosphatase level J:211773
abnormal duodenum morphology J:211773
abnormal ileum morphology J:211773
abnormal jejunum morphology J:211773
abnormal lymph node morphology J:211773
abnormal pancreas morphology J:211773
abnormal salivary gland morphology J:211773
enlarged lymph nodes J:211773
increased circulating amylase level J:211773
Cadps2tm1Bros/Cadps2tm1Bros
Not Specified 		abnormal pancreatic beta cell physiology J:131014
abnormal pancreatic somatostatin secretion J:131014
decreased insulin secretion J:131014
impaired glucose tolerance J:131014
increased glucagon secretion J:131014
increased insulin sensitivity J:131014
Cadps2tm1Tfr/Cadps2+
C57BL/6-Cadps2tm1Tfr 		abnormal maternal nurturing J:121256
decreased exploration in new environment J:121256
Cadps2tm1Tfr/Cadps2tm1Tfr
C57BL/6-Cadps2tm1Tfr 		abnormal brain interneuron morphology J:121256
abnormal brain morphology J:121256
abnormal cerebellar granule cell migration J:120106
abnormal cerebellum external granule cell layer morphology J:120106
abnormal cerebellum fissure morphology J:120106
abnormal cerebellum morphology J:120106
abnormal circadian behavior J:121256
abnormal emotion/affect behavior J:121256
abnormal maternal nurturing J:121256
abnormal neuron specification J:120106
abnormal optokinetic reflex J:120106
abnormal paired-pulse facilitation J:120106
abnormal Purkinje cell dendrite morphology J:120106
abnormal response to novel object J:121256
abnormal sleep pattern J:121256
abnormal social investigation J:121256
abnormal social/conspecific interaction behavior J:121256
abnormal spatial reference memory J:121256
decreased body weight J:121256
decreased exploration in new environment J:121256
decreased Purkinje cell number J:121256
hyperactivity J:121256
impaired coordination J:120106
increased anxiety-related response J:121256
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory