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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Bptf
bromodomain PHD finger transcription factor
MGI:2444008
50 phenotypes from 6 alleles in 9 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Bptfem1(IMPC)Bay/Bptf+
C57BL/6N-Bptfem1(IMPC)Bay/Bay 		abnormal bone structure J:211773
decreased body length J:211773
decreased prepulse inhibition J:211773
vertebral fusion J:211773
Bptfem1(IMPC)Bay/Bptfem1(IMPC)Bay
C57BL/6N-Bptfem1(IMPC)Bay/Bay 		preweaning lethality, complete penetrance J:211773
preweaning lethality, incomplete penetrance J:211773
Bptfem1Zfa/Bptfem1Zfa
Lgr5tm1(cre/ERT2)Cle/Lgr5+
involves: 129P2/OlaHsd * C57BL/6 		abnormal digestive system development J:268724
Bptfem1Zfa/Bptfem1Zfa
Tg(Rorc-cre)1Litt/0
involves: C57BL/6 * FVB 		decreased common lymphocyte progenitor cell number J:259392
increased susceptibility to bacterial infection J:259392
increased susceptibility to bacterial infection induced morbidity/mortality J:259392
BptfGt(A012C04)Wrst/BptfGt(A012C04)Wrst
either: 129S2/SvPas-BptfGt(A012C04)Wrst or B6.129S2-BptfGt(A012C04)Wrst or (involves: 129S2/SvPas * CD-1) 		abnormal chorion morphology J:142592
abnormal developmental patterning J:142592
abnormal egg cylinder morphology J:142592
abnormal extraembryonic tissue morphology J:142592
abnormal primitive streak elongation J:142592
abnormal primitive streak formation J:142592
abnormal proximal-distal axis patterning J:142592
abnormal rostral-caudal axis patterning J:142592
abnormal visceral endoderm morphology J:142592
absent chorion J:142592
decreased embryo size J:142592
embryonic growth arrest J:142592
embryonic growth retardation J:142592
embryonic lethality during organogenesis, complete penetrance J:142592
small ectoplacental cone J:142592
thick embryonic epiblast J:142592
BptfGt(XG023)Byg/BptfGt(XG023)Byg
involves: 129P2/OlaHsd 		abnormal rostral-caudal axis patterning J:147414
absent anterior visceral endoderm J:147414
absent distal visceral endoderm J:147414
absent mesoderm J:147414
decreased cell proliferation J:147414
embryonic growth arrest J:147414
embryonic lethality between implantation and somite formation, complete penetrance J:147414
failure of primitive streak formation J:147414
BptfGt(XG023)Byg/Bptftm1.2Cwu
involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 		embryonic growth arrest J:147414
embryonic lethality between implantation and somite formation, complete penetrance J:147414
Bptftm1.1Cwu/Bptftm1.1Cwu
Emx1tm1(cre)Krj/Emx1+
involves: 129S1/Sv * 129S2/SvPas * C57BL/6 		abnormal cerebral cortex morphology J:334252
abnormal head shape J:334252
abnormal neuron specification J:334252
abnormal neuronal precursor proliferation J:334252
abnormal stratification in cerebral cortex J:334252
normal behavior/neurological phenotype J:334252
decreased body weight J:334252
decreased brain weight J:334252
decreased forebrain size J:334252
decreased neuronal precursor cell number J:334252
forebrain hypoplasia J:334252
increased neuron apoptosis J:334252
microgliosis J:334252
normal mortality/aging J:334252
Bptftm1.1Cwu/Bptftm1.1Cwu
Foxg1tm1(cre)Skm/?
involves: 129P2/OlaHsd-Hprtb-m3 * 129S1/Sv-Oca2+ Tyr+ Kitl+ 		abnormal olfactory sensory neuron morphology J:217534
perinatal lethality, complete penetrance J:217534
Bptftm1.2Cwu/Bptftm1.2Cwu
involves: 129S1/Sv * C57BL/6 		abnormal ectoderm development J:147414
abnormal endoderm development J:147414
absent mesoderm J:147414
decreased embryo size J:147414
embryonic lethality between implantation and somite formation, complete penetrance J:147414
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory