Cachd1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cachd1
cache domain containing 1
MGI:2444177

24 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cachd1^em1(IMPC)J/Cachd1⁺ C57BL/6NJ-Cachd1^em1(IMPC)J/J	decreased grip strength	J:211773
Cachd1^em1(IMPC)J/Cachd1⁺ C57BL/6NJ-Cachd1^em1(IMPC)J/J	increased circulating calcium level	J:211773
Cachd1^em1(IMPC)J/Cachd1^em1(IMPC)J C57BL/6NJ-Cachd1^em1(IMPC)J/J	preweaning lethality, incomplete penetrance	J:211773
Cachd1^em1Kjn/Cachd1^em1Kjn C57BL/6J-Cachd1^em1Kjn/KjnJ	abnormal cochlear endolymph ionic homeostasis	J:314293
	abnormal distortion product otoacoustic emission	J:314293
	abnormal endolymph physiology	J:314293
	abnormal inner ear development	J:314293
	abnormal inner ear morphology	J:314293
	abnormal membranous labyrinth morphology	J:314293
	abnormal organ of Corti morphology	J:314293
	abnormal scala media morphology	J:314293
	abnormal tectorial membrane morphology	J:314293
	abnormal utricle morphology	J:314293
	abnormal vestibular saccule morphology	J:314293
	circling	J:314293
	decreased cochlear outer hair cell number	J:314293
	decreased endocochlear potential	J:314293
	decreased otolith number	J:314293
	dilated endolymphatic duct	J:314293
	head tilt	J:314293
	increased endolymph production	J:314293
	increased or absent threshold for auditory brainstem response	J:314293
	small temporal bone	J:314293
Cachd1^tow/Cachd1^tow B6(Cg)-Cachd1^tow/GrsrKjn	abnormal inner ear development	J:314293
	abnormal inner ear morphology	J:314293
	abnormal utricle morphology	J:314293
	abnormal vestibular saccule morphology	J:314293
	circling	J:314293
	decreased otolith number	J:314293
	head tilt	J:314293
	impaired swimming	J:314293
	increased or absent threshold for auditory brainstem response	J:314293

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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