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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gcn1
GCN1 activator of EIF2AK4
MGI:2444248
23 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gcn1em1(IMPC)J/Gcn1+
C57BL/6NJ-Gcn1em1(IMPC)J/Mmjax 		decreased circulating bilirubin level J:211773
increased circulating glucose level J:211773
Gcn1em1(IMPC)J/Gcn1em1(IMPC)J
C57BL/6NJ-Gcn1em1(IMPC)J/Mmjax 		preweaning lethality, complete penetrance J:211773
Gcn1em1Itohk/Gcn1em1Itohk
involves: C57BL/6 		decreased embryo size J:287528
embryonic growth retardation J:287528
embryonic lethality, complete penetrance J:287528
Gcn1em2Itohk/Gcn1em2Itohk
C57BL/6-Gcn1em2Itohk 		abnormal cell cycle checkpoint function J:287528
abnormal cell morphology J:287528
abnormal fibroblast physiology J:287528
abnormal head morphology J:287528
anencephaly J:287528
atelectasis J:287528
decreased embryo size J:287528
decreased fetal size J:287528
decreased fetal weight J:287528
decreased fibroblast proliferation J:287528
delayed limb development J:287528
embryonic growth retardation J:287528
exophthalmos J:287528
eyelid hypoplasia J:287528
fetal growth retardation J:287528
increased mitotic index J:287528
mandible hypoplasia J:287528
perinatal lethality, complete penetrance J:287528
respiratory failure J:287528
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory