Ube2o Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ube2o
ubiquitin-conjugating enzyme E2O
MGI:2444266

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ube2o^{tm1.1(KOMP)Mbp}/Ube2o⁺ Tg(TRAMP)8247Ng/0 involves: C57BL/6 * C57BL/6N * FVB/N	decreased tumor growth/size	J:239679
Ube2o^{tm1.1(KOMP)Mbp}/Ube2o⁺ Tg(MMTV-PyVT)634Mul/0 involves: C57BL/6 * C57BL/6N * FVB/N	decreased tumor growth/size	J:239679
	increased tumor latency	J:239679
	increased tumor-free survival time	J:239679
Ube2o^{tm1.1(KOMP)Mbp}/Ube2o^{tm1.1(KOMP)Mbp} Pten^tm1Ppp/Pten^tm1Ppp involves: 129S1/Sv * C57BL/6 * C57BL/6N * FVB/N	increased lymphoma incidence	J:239679
Ube2o^{tm1.1(KOMP)Mbp}/Ube2o^{tm1.1(KOMP)Mbp} Tg(IghMyc)22Bri/0 involves: C57BL * C57BL/6N * FVB/N * SJL	decreased survivor rate	J:239679
	increased B cell derived lymphoma incidence	J:239679
Ube2o^{tm1.1(KOMP)Mbp}/Ube2o^{tm1.1(KOMP)Mbp} Tg(MMTV-PyVT)634Mul/0 involves: C57BL/6 * C57BL/6N * FVB/N	decreased tumor growth/size	J:239679
	increased tumor latency	J:239679
	increased tumor-free survival time	J:239679
	mammary gland hypoplasia	J:239679
Ube2o^{tm1.1(KOMP)Mbp}/Ube2o^{tm1.1(KOMP)Mbp} Tg(TRAMP)8247Ng/0 involves: C57BL/6 * C57BL/6N * FVB/N	decreased metastatic potential	J:239679
	decreased tumor growth/size	J:239679
	normal endocrine/exocrine gland phenotype	J:239679

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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