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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dennd5b
DENN domain containing 5B
MGI:2444273
42 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dennd5bem1(IMPC)Tcp/Dennd5bem1(IMPC)Tcp
C57BL/6N-Dennd5bem1(IMPC)Tcp/Tcp 		abnormal bone structure J:211773
abnormal seminal vesicle morphology J:211773
abnormal spleen morphology J:211773
abnormal sternum morphology J:211773
decreased bone mineral content J:211773
decreased bone mineral density J:211773
decreased circulating cholesterol level J:211773
decreased circulating glucose level J:211773
decreased circulating HDL cholesterol level J:211773
decreased circulating total protein level J:211773
decreased circulating triglyceride level J:211773
decreased exploration in new environment J:211773
decreased heart rate J:211773
decreased red blood cell distribution width J:211773
decreased total body fat amount J:211773
improved glucose tolerance J:211773
increased circulating alkaline phosphatase level J:211773
increased freezing behavior J:211773
increased grip strength J:211773
increased lean body mass J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
prolonged PR interval J:211773
prolonged QT interval J:211773
prolonged RR interval J:211773
Dennd5bem1Smgo/Dennd5bem1Smgo
involves: C57BL/6 * CBA 		abnormal body mass index J:276600
abnormal circulating lipid level J:276600
abnormal digestive system physiology J:276600
abnormal duodenum morphology J:276600
abnormal intestine physiology J:276600
abnormal small intestine morphology J:276600
decreased body fat mass J:276600
decreased circulating HDL cholesterol level J:276600
decreased liver cholesterol level J:276600
decreased liver free fatty acids level J:276600
decreased susceptibility to atherosclerosis J:276600
decreased susceptibility to weight gain J:276600
distended duodenum J:276600
distended ileum J:276600
distended jejunum J:276600
increased circulating VLDL triglyceride level J:276600
increased lean body mass J:276600
increased small intestine length J:276600
Dennd5bm1Anu/Dennd5bm1Anu
C57BL/6NCrlAnu-Dennd5bm1Anu 		normal immune system phenotype J:104190
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory