Nalcn Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nalcn
sodium leak channel, non-selective
MGI:2444306

22 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nalcn^Drl/Nalcn⁺ involves: C57BL/6J * C57BL/6N	abnormal brain wave pattern	J:236598
	abnormal circadian behavior	J:236598
	abnormal nervous system electrophysiology	J:236598
	abnormal paradoxical sleep pattern	J:236598
	normal behavior/neurological phenotype	J:236598
Nalcn^em1(IMPC)Mbp/Nalcn⁺ C57BL/6N-Nalcn^em1(IMPC)Mbp/Ucd	abnormal kidney morphology	J:211773
	abnormal spleen morphology	J:211773
	decreased lymphocyte cell number	J:211773
	enlarged spleen	J:211773
	hemorrhage	J:211773
	increased neutrophil cell number	J:211773
	spina bifida	J:211773
Nalcn^em1(IMPC)Mbp/Nalcn^em1(IMPC)Mbp C57BL/6N-Nalcn^em1(IMPC)Mbp/Ucd	hemorrhage	J:211773
	preweaning lethality, complete penetrance	J:211773
	spina bifida	J:211773
Nalcn^em1Iiis/Nalcn⁺ Not Specified	abnormal paradoxical sleep pattern	J:236598
Nalcn^tm1.1Dren/Nalcn^tm1.1Dren involves: C57BL/6	abnormal breathing pattern	J:141581
	abnormal channel response	J:141581
	abnormal nerve conduction	J:141581
	abnormal nervous system electrophysiology	J:141581
	apnea	J:141581
	normal behavior/neurological phenotype	J:141581
	decreased physiological sensitivity to xenobiotic	J:141581
	normal embryo phenotype	J:141581
	neonatal lethality, complete penetrance	J:141581
Nalcn^{tm1c(KOMP)Wtsi}/Nalcn^{tm1c(KOMP)Wtsi} Tg(Camk2a-cre)2Gsc/0 involves: C57BL/6N * FVB/N	abnormal nervous system electrophysiology	J:238767
	impaired ability to fire action potentials	J:238767
	lethality at weaning, complete penetrance	J:238767

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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