Atg4d Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Atg4d
autophagy related 4D, cysteine peptidase
MGI:2444308

14 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Atg4d^{Gt(OST254045)Lex}/Atg4d^{Gt(OST254045)Lex} Tg(CAG-EGFP/Map1lc3b)53Nmz/0 involves: 129S5/SvEvBrd * C57BL/6J * C57BL/6NCrlj * DBA/2J	abnormal autophagosome formation	J:313858
	abnormal cerebellar molecular layer	J:313858
	abnormal Purkinje cell morphology	J:313858
	ataxia	J:313858
	decreased grip strength	J:313858
	gliosis	J:313858
	impaired coordination	J:313858
	impaired long-term object recognition memory	J:313858
	increased thigmotaxis	J:313858
	limb grasping	J:313858
	long stride length	J:313858
	neurodegeneration	J:313858
	Purkinje cell degeneration	J:313858
	thin cerebellar molecular layer	J:313858

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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