Frem2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Frem2
Fras1 related extracellular matrix protein 2
MGI:2444465

60 phenotypes from 9 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Frem2^b2b1562Clo/Frem2^b2b1562Clo C57BL/6J-Frem2^b2b1562Clo	absent kidney	J:175213
	cryptophthalmos	J:175213
	polydactyly	J:175213
	syndactyly	J:175213
Frem2^b2b3270Clo/Frem2^b2b3270Clo C57BL/6J-Frem2^b2b3270Clo	anophthalmia	J:175213
	diaphragmatic hernia	J:175213
	microphthalmia	J:175213
	right aortic arch	J:175213
Frem2^em1Hali/Frem2^em2Hali C57BL/6J-Frem2^em1Hali Frem2^em2Hali	abnormal anterior eye segment morphology	J:279933
	abnormal cornea morphology	J:279933
	abnormal eye morphology	J:279933
	abnormal lens morphology	J:279933
	absent ciliary body	J:279933
	acoria	J:279933
	cornea vascularization	J:279933
	cryptophthalmos	J:279933
	increased total retina thickness	J:279933
	iris hypoplasia	J:279933
	iris synechia	J:279933
	single kidney	J:279933
	syndactyly	J:279933
Frem2^em2Hali/Frem2^em2Hali C57BL/6J-Frem2^em2Hali	cryptophthalmos	J:279933
	normal limbs/digits/tail phenotype	J:279933
	single kidney	J:279933
Frem2^{Gt(KST252)Byg}/Frem2^my-Ucl involves: 129P2/OlaHsd * CD-1 * NMRI	bleb	J:98344
Frem2^my-F11/Frem2^my-F11 either: (involves: C3HeB/FeJ * C57BL/6J) or (involves: C3HeB/FeJ * C57BL/6J * M. m. castaneus)	abnormal coat/hair pigmentation	J:101189
	abnormal digit morphology	J:101189
	abnormal head morphology	J:101189
	abnormal heart valve morphology	J:101189
	abnormal limb morphology	J:101189
	abnormal lung morphology	J:101189
	absent outer ear	J:101189
	anophthalmia	J:101189
	atrial septal defect	J:101189
	decreased birth weight	J:101189
	hemorrhage	J:101189
	microphthalmia	J:101189
	neonatal lethality, incomplete penetrance	J:101189
	oligodactyly	J:101189
	open neural tube	J:101189
	small ears	J:101189
	sparse hair	J:101189
	syndactyly	J:101189
	variable body spotting	J:101189
Frem2^my-Ucl/Frem2^my-Ucl involves: NMRI	cryptophthalmos	J:98344
	fetal bleb	J:98344
	prenatal lethality, incomplete penetrance	J:98344
	syndactyly	J:98344
Frem2^my/Frem2^my involves: MY/HuLeJ * C57BL/6	absent kidney	J:111788
	bleb	J:111788
	cryptophthalmos	J:111788
	syndactyly	J:111788
Frem2^my/Frem2^my Not Specified	abnormal craniofacial development	J:14847
	abnormal embryo development	J:20762
	abnormal eye development	J:14847, J:20762
	abnormal facial morphology	J:14847
	abnormal limb morphology	J:14847
	abnormal skin morphology	J:20762
	absent kidney	J:20762
	acrania	J:20762
	bleb	J:14847
	clubfoot	J:20762
	eye bleb	J:14847
	hydrocephaly	J:14847
	meroanencephaly	J:20762
	perinatal lethality, incomplete penetrance	J:14847
	preaxial polydactyly	J:20762
	short face	J:14847
	short snout	J:14847
	syndactyly	J:20762
Frem2^ne/Frem2^ne STOCK Frem2^ne/GrsrJ	abnormal ear shape	J:136583
	abnormal eyelid morphology	J:136583
	normal cardiovascular system phenotype	J:136583
	cryptophthalmos	J:136583
	decreased litter size	J:136583
	fused phalanges	J:136583
	irregular coat pigmentation	J:136583
	microphthalmia	J:136583
	normal renal/urinary system phenotype	J:136583
	syndactyly	J:136583

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24