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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nlgn3
neuroligin 3
MGI:2444609
16 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Nlgn1tm1.1Sud/Nlgn1tm1.1Sud
Nlgn2tm1.1Sud/Nlgn2tm1.1Sud
Nlgn3tm4.1Sud/Y
Tg(Pcp2-cre)2Mpin/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac 		abnormal CNS synaptic transmission J:227671
abnormal inhibitory postsynaptic currents J:227671
abnormal miniature inhibitory postsynaptic currents J:227671
abnormal synapse morphology J:227671
abnormal synaptic bouton morphology J:227671
decreased excitatory postsynaptic current amplitude J:227671
decreased miniature inhibitory postsynaptic current amplitude J:227671
decreased miniature inhibitory postsynaptic current frequency J:227671
Nlgn1tm1.1Sud/Nlgn1tm1.1Sud
Nlgn3tm4.1Sud/Y
Tg(Pcp2-cre)2Mpin/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac 		abnormal synapse morphology J:227671
decreased excitatory postsynaptic current amplitude J:227671
normal nervous system phenotype J:227671
Nlgn1tm1Bros/Nlgn1tm1Bros
Nlgn2tm1Bros/Nlgn2tm1Bros
Nlgn3tm1Bros/Nlgn3tm1Bros
Not Specified 		abnormal nervous system development J:113647
abnormal pre-Botzinger complex physiology J:113647
abnormal respiration J:113647
decreased body weight J:113647
neonatal lethality, complete penetrance J:113647
Nlgn1tm1Bros/Nlgn1tm1Bros
Nlgn3tm1Bros/Nlgn3tm1Bros
Not Specified 		abnormal CNS synaptic transmission J:113647
abnormal parental behavior J:113647
reduced fertility J:113647
Nlgn2tm1.1Sud/Nlgn2tm1.1Sud
Nlgn3tm4.1Sud/Y
Tg(Pcp2-cre)2Mpin/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac 		abnormal miniature inhibitory postsynaptic currents J:227671
abnormal synapse morphology J:227671
decreased excitatory postsynaptic current amplitude J:227671
decreased miniature inhibitory postsynaptic current amplitude J:227671
decreased miniature inhibitory postsynaptic current frequency J:227671
normal nervous system phenotype J:227671
Nlgn2tm1Bros/Nlgn2tm1Bros
Nlgn3tm1Bros/Nlgn3tm1Bros
Not Specified 		abnormal CNS synaptic transmission J:113647
abnormal parental behavior J:113647
reduced fertility J:113647
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory