Dmxl2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dmxl2
Dmx-like 2
MGI:2444630

32 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dmxl2^{tm1a(EUCOMM)Wtsi}/Dmxl2⁺ C57BL/6N-A^tm1Brd Dmxl2^{tm1a(EUCOMM)Wtsi}/WtsiH	decreased bone mineral content	J:211773
	decreased circulating cholesterol level	J:211773
	decreased lean body mass	J:211773
	increased total body fat amount	J:211773
Dmxl2^{tm1a(EUCOMM)Wtsi}/Dmxl2⁺ involves: C57BL/6N	no abnormal phenotype detected	J:217623
Dmxl2^{tm1a(EUCOMM)Wtsi}/Dmxl2^{tm1a(EUCOMM)Wtsi} C57BL/6N-A^tm1Brd Dmxl2^{tm1a(EUCOMM)Wtsi}/WtsiH	abnormal ductus venosus valve morphology	J:239583
	abnormal vertebral artery morphology	J:239583
	blood in lymph vessels	J:239583
	embryo tumor	J:239583
	multiple persisting craniopharyngeal ducts	J:239583
	no abnormal phenotype detected	J:239583
	preweaning lethality, complete penetrance	J:211773
Dmxl2^{tm1a(EUCOMM)Wtsi}/Dmxl2^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	prenatal lethality, complete penetrance	J:217623
Dmxl2^{tm1c(EUCOMM)Wtsi}/Dmxl2⁺ Tg(Nes-cre)1Atp/0 involves: C57BL/6N * FVB/N	abnormal estrous cycle	J:217623
	abnormal hypothalamus secretion	J:217623
	decreased body weight	J:217623
	decreased circulating testosterone level	J:217623
	decreased corpora lutea number	J:217623
	decreased gonadotropin-releasing hormone neuron number	J:217623
	decreased ovary weight	J:217623
	decreased ovulation rate	J:217623
	decreased testis weight	J:217623
	delayed estrous cycle	J:217623
	delayed sexual maturation	J:217623
	delayed vaginal opening	J:217623
	normal homeostasis/metabolism phenotype	J:217623
	increased circulating luteinizing hormone level	J:217623
	increased exploration in new environment	J:217623
	reduced female fertility	J:217623
	reduced fertility	J:217623
	reduced male fertility	J:217623
	short perineum	J:217623
	short proestrus	J:217623

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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