Fnip1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fnip1
folliculin interacting protein 1
MGI:2444668

14 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Atg3^tm1.1Ywh/Atg3^tm1.1Ywh Fnip1^m1Btlr/Fnip1^m1Btlr Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺ involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal autophagy	J:234285
	absent B cells	J:234285
Flcn^tm1Baba/Flcn^tm1Baba Fnip1^tm1.1Baba/Fnip1^tm1.1Baba Fnip2^tm1.1Lss/Fnip2^tm1.1Lss Tg(Cdh16-cre)91Igr/0 involves: C57BL/6 * ICR	enlarged kidney	J:220672
	polycystic kidney	J:220672
Fnip1^{Gt(RRM154)Byg}/Fnip1^{Gt(RRM154)Byg} Igh^tm2Cgn/Igh^tm2Cgn involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL	absent B cells	J:189078
	absent B-2 B cells	J:189078
	decreased B-1 B cell number	J:189078
Fnip1^{Gt(RRM154)Byg}/Fnip1^{Gt(RRM154)Byg} Tg(BCL2)22Wehi/0 involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL	increased B cell number	J:189078
Fnip1^{Gt(RRM154)Byg}/Fnip1^{Gt(RRM154)Byg} Tg(IghelMD4)4Ccg/0 involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL	absent B cells	J:189078
	absent B-2 B cells	J:189078
	decreased B-1 B cell number	J:189078
	increased immature B cell number	J:189078
Fnip1^LPAB.1/Fnip1^LPAB.1 Tg(IghMyc)22Bri/0 involves: C57BL * C57BL/6J * SJL	increased B cell apoptosis	J:187318
	normal neoplasm	J:187318
Fnip1^m1Btlr/Fnip1^m1Btlr Prkag2^tm1.1Geno/Prkag2^tm1.1Geno Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ involves: 129 * C57BL/6 * C57BL/6J * CBA	normal cardiovascular system phenotype	J:256296
Fnip1^tm1.1Baba/Fnip1^tm1.1Baba Fnip2^tm1.1Lss/Fnip2^tm1.1Lss Tg(Cdh16-cre)91Igr/0 involves: C57BL/6 * ICR	abnormal mitochondrial physiology	J:220672
	enlarged kidney	J:220672
	polycystic kidney	J:220672
	postnatal lethality, complete penetrance	J:220672
Fnip1^tm1.2Baba/Fnip1⁺ Fnip2^tm1.2Lss/Fnip2^tm1.2Lss involves: C57BL/6	increased kidney tumor incidence	J:220672
Fnip1^tm1.2Baba/Fnip1^tm1.2Baba Igh^tm2Cgn/Igh^tm2Cgn involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL	absent B cells	J:189078
	absent B-2 B cells	J:189078
	decreased B-1 B cell number	J:189078
Fnip1^tm1.2Baba/Fnip1^tm1.2Baba Tg(BCL2)22Wehi/0 involves: C57BL/6 * FVB/N * SJL	increased B cell number	J:189078
Fnip1^tm1.2Baba/Fnip1^tm1.2Baba Tg(IghelMD4)4Ccg/0 involves: C57BL/6 * C57BL/6J * FVB/N * SJL	absent B cells	J:189078
	absent B-2 B cells	J:189078
	decreased B-1 B cell number	J:189078
	increased immature B cell number	J:189078

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24