Nipal4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nipal4
NIPA-like domain containing 4
MGI:2444671

21 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Nipal4^tm1Akih/Nipal4^tm1Akih involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj	abnormal corneocyte morphology	J:261184
	abnormal epidermal lamellar body morphology	J:261184
	abnormal epidermis stratum granulosum morphology	J:261184
	abnormal keratinocyte differentiation	J:261184
	abnormal keratohyalin granule morphology	J:261184
	abnormal magnesium ion homeostasis	J:261184
	abnormal skin appearance	J:261184
	abnormal stratum corneum lipid matrix formation	J:261184
	decreased birth weight	J:261184
	decreased ceramide level	J:261184
	decreased keratohyalin granule size	J:261184
	decreased sphingosine level	J:261184
	hyperkeratosis	J:261184
	impaired skin barrier function	J:261184
	increased ceramide level	J:261184
	increased keratohyalin granule number	J:261184
	increased sphingosine level	J:261184
	neonatal lethality, complete penetrance	J:261184
	shiny skin	J:261184
	thick epidermis stratum spinosum	J:261184
	weight loss	J:261184

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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