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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ptrh2
peptidyl-tRNA hydrolase 2
MGI:2444848
28 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Meox2tm1(cre)Sor/Meox2+
Ptrh2tm1Eruo/Ptrh2tm1.1Eruo
B6.Cg-Ptrh2tm1Eruo Ptrh2tm1.1Eruo Meox2tm1(cre)Sor 		abnormal cerebral cortex morphology J:220518
abnormal hepatocyte morphology J:220518
abnormal muscle fiber morphology J:220518
abnormal pancreatic acinar cell morphology J:220518
ataxia J:220518
cachexia J:220518
cerebellum atrophy J:220518
decreased brain weight J:220518
exocrine pancreatic insufficiency J:220518
muscle weakness J:220518
postnatal growth retardation J:220518
postnatal lethality, complete penetrance J:220518
Ptrh2tm1.1Eruo/Ptrh2tm1.1Eruo
C57BL/6-Ptrh2tm1.1Eruo 		abnormal epaxial muscle morphology J:131853
abnormal sarcolemma morphology J:241883
ataxia J:131853
cachexia J:131853
centrally nucleated skeletal muscle fibers J:241883
decreased fibroblast apoptosis J:131853
decreased neutrophil cell number J:131853
delayed kidney development J:131853
dystrophic muscle J:241883
impaired righting response J:241883
increased creatine kinase activity J:241883
increased variability of skeletal muscle fiber size J:241883
joint contracture J:241883
myopathy J:241883
postnatal lethality, complete penetrance J:131853, J:241883
progressive muscle weakness J:131853, J:241883
skeletal muscle degeneration J:241883
skeletal muscle endomysial fibrosis J:241883
Ptrh2tm1Eruo/Ptrh2tm1Eruo
C57BL/6-Ptrh2tm1Eruo 		no abnormal phenotype detected J:131853
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory