Chfr Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Chfr
checkpoint with forkhead and ring finger domains
MGI:2444898

20 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Chfr^{tm1a(KOMP)Wtsi}/Chfr^{tm1a(KOMP)Wtsi} C57BL/6NCrl-Chfr^{tm1a(KOMP)Wtsi}/Ccpcz	abnormal coat/hair pigmentation	J:211773
	abnormal inspiratory capacity	J:211773
	abnormal skin coloration	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	decreased heart rate	J:211773
	decreased lung elastance	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased kidney weight	J:211773
	increased lung compliance	J:211773
	small testis	J:211773
	thin ventricular wall	J:211773
Chfr^tm1Jc/Chfr⁺ involves: 129S/SvEv * C57BL/6	increased incidence of tumors by chemical induction	J:97428
	increased lymphoma incidence	J:97428
	increased tumor incidence	J:97428
	premature death	J:97428
Chfr^tm1Jc/Chfr^tm1Jc involves: 129S/SvEv * C57BL/6	abnormal mitosis	J:97428
	chromosome breakage	J:97428
	increased incidence of tumors by chemical induction	J:97428
	increased lymphoma incidence	J:97428
	increased tumor incidence	J:97428
	premature death	J:97428

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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