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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ppargc1b
peroxisome proliferative activated receptor, gamma, coactivator 1 beta
MGI:2444934
20 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ppargc1atm1Dpk/Ppargc1atm1Dpk
Ppargc1btm1.1Dpk/Ppargc1b+
involves: 129X1/SvJ * FVB/N 		impaired adaptive thermogenesis J:137598
Ppargc1atm1Dpk/Ppargc1atm1Dpk
Ppargc1btm1.1Dpk/Ppargc1btm1.1Dpk
involves: 129X1/SvJ * FVB/N 		abnormal blood circulation J:137598
abnormal brown adipose tissue morphology J:137598
abnormal fat cell morphology J:137598
abnormal heart development J:137598
abnormal heart left ventricle morphology J:137598
abnormal myocardium layer morphology J:137598
abnormal pulmonary alveolus morphology J:137598
congestive heart failure J:137598
decreased body weight J:137598
decreased cardiac output J:137598
decreased circulating glucose level J:137598
decreased heart left ventricle weight J:137598
decreased heart rate J:137598
decreased triglyceride level J:137598
neonatal lethality, incomplete penetrance J:137598
postnatal lethality, complete penetrance J:137598
respiratory distress J:137598
small heart J:137598
Ppargc1atm1Dpk/Ppargc1atm1Dpk
Ppargc1btm1Dpk/Ppargc1btm1Dpk
Tg(Myh6-cre)2182Mds/0
involves: 129X1/SvJ * FVB/N 		abnormal myocardium layer morphology J:137598
decreased cardiac output J:137598
neonatal lethality, incomplete penetrance J:137598
postnatal lethality, complete penetrance J:137598
Ppargc1atm2Brsp/Ppargc1atm2Brsp
Ppargc1btm1Dpk/Ppargc1btm1Dpk
Tg(Tyr-cre)1Lru/0
involves: 129 * 129X1/SvJ * C57BL/6 		normal pigmentation phenotype J:194191
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory