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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Arhgap1
Rho GTPase activating protein 1
MGI:2445003
35 phenotypes from 1 allele in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Arhgap1tm1Yizh/Arhgap1tm1Yizh
involves: 129S6/SvEvTac 		abnormal cell morphology J:101418
decreased embryo size J:101418
increased apoptosis J:101418
increased fibroblast apoptosis J:101418
increased neuron apoptosis J:101418
liver hypoplasia J:101418
postnatal growth retardation J:101418
postnatal lethality J:101418
spleen hypoplasia J:101418
thymus hypoplasia J:101418
Arhgap1tm1Yizh/Arhgap1tm1Yizh
involves: 129S6/SvEvTac * C57BL/6 		abnormal chromosome morphology J:119516
abnormal DNA repair J:119516
abnormal hair growth J:119516
abnormal hematopoietic stem cell morphology J:119516
abnormal hematopoietic system morphology/development J:119516
abnormal vertebral body morphology J:119516
absent subcutaneous adipose tissue J:119516
anemia J:119516
decreased body weight J:119516
decreased bone marrow cell number J:119516
decreased bone mineral density J:119516
decreased bone mineral density of femur J:119516
decreased femur compact bone thickness J:119516
decreased fibroblast proliferation J:119516
decreased spleen white pulp amount J:119516
impaired wound healing J:119516
kyphosis J:119516
liver hypoplasia J:119516
lordokyphosis J:119516
muscular atrophy J:119516
neonatal lethality, incomplete penetrance J:119516
osteoporosis J:119516
premature aging J:119516
premature death J:119516
reduced fertility J:119516
renal hypoplasia J:119516
spleen hypoplasia J:119516
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory