Arhgap1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arhgap1
Rho GTPase activating protein 1
MGI:2445003

35 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arhgap1^tm1Yizh/Arhgap1^tm1Yizh involves: 129S6/SvEvTac	abnormal cell morphology	J:101418
	decreased embryo size	J:101418
	increased apoptosis	J:101418
	increased fibroblast apoptosis	J:101418
	increased neuron apoptosis	J:101418
	liver hypoplasia	J:101418
	postnatal growth retardation	J:101418
	postnatal lethality	J:101418
	spleen hypoplasia	J:101418
	thymus hypoplasia	J:101418
Arhgap1^tm1Yizh/Arhgap1^tm1Yizh involves: 129S6/SvEvTac * C57BL/6	abnormal chromosome morphology	J:119516
	abnormal DNA repair	J:119516
	abnormal hair growth	J:119516
	abnormal hematopoietic stem cell morphology	J:119516
	abnormal hematopoietic system morphology/development	J:119516
	abnormal vertebral body morphology	J:119516
	absent subcutaneous adipose tissue	J:119516
	anemia	J:119516
	decreased body weight	J:119516
	decreased bone marrow cell number	J:119516
	decreased bone mineral density	J:119516
	decreased bone mineral density of femur	J:119516
	decreased femur compact bone thickness	J:119516
	decreased fibroblast proliferation	J:119516
	decreased spleen white pulp amount	J:119516
	impaired wound healing	J:119516
	kyphosis	J:119516
	liver hypoplasia	J:119516
	lordokyphosis	J:119516
	muscular atrophy	J:119516
	neonatal lethality, incomplete penetrance	J:119516
	osteoporosis	J:119516
	premature aging	J:119516
	premature death	J:119516
	reduced fertility	J:119516
	renal hypoplasia	J:119516
	spleen hypoplasia	J:119516

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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