Clspn Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Clspn
claspin
MGI:2445153

27 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Clspn^{tm1(KOMP)Vlcg}/Clspn⁺ C57BL/6N-Clspn^{tm1(KOMP)Vlcg}	abnormal DNA repair	J:332163
	abnormal embryo development	J:332163
	abnormal female meiosis I arrest	J:332163
	abnormal intestine morphology	J:332163
	abnormal limb morphology	J:332163
	abnormal pregnancy	J:332163
	decreased litter size	J:332163
	decreased tumor latency	J:332163
	delayed female fertility	J:332163
	embryonic growth arrest	J:332163
	enhanced liver regeneration	J:332163
	impaired polar body extrusion	J:332163
	increased B cell number	J:332163
	increased bone marrow cell number	J:332163
	increased hepatocyte proliferation	J:332163
	increased incidence of tumors by chemical induction	J:332163
	increased liver weight	J:332163
	increased susceptibility to age-related hepatic steatosis	J:332163
	increased susceptibility to diet-induced hepatic steatosis	J:332163
	increased susceptibility to injury	J:332163
	increased susceptibility to weight gain	J:332163
	lymphoid hyperplasia	J:332163
	maternal effect	J:332163
	reduced female fertility	J:332163
	normal reproductive system phenotype	J:332163
Clspn^{tm1(KOMP)Vlcg}/Clspn^{tm1(KOMP)Vlcg} C57BL/6N-Clspn^{tm1(KOMP)Vlcg}	embryonic lethality during organogenesis, complete penetrance	J:332163
Clspn^{tm1(KOMP)Vlcg}/Clspn^{tm1(KOMP)Vlcg} C57BL/6N-Clspn^{tm1(KOMP)Vlcg}/Rbrc	preweaning lethality, complete penetrance	J:211773
Clspn^tm1.1Hmas/Clspn^tm1.1Hmas Not Specified	embryonic lethality during organogenesis, complete penetrance	J:240838

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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