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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Flnb
filamin, beta
MGI:2446089
85 phenotypes from 6 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
FlnbGt(BGB085)Byg/FlnbGt(BGB085)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal angiogenesis J:120066
abnormal artery development J:120066
abnormal brain vasculature morphology J:120066
abnormal cell physiology J:120066
abnormal hyaline cartilage morphology J:120066
abnormal middle cerebral artery morphology J:120066
abnormal motor capabilities/coordination/movement J:120066
abnormal posture J:120066
abnormal vertebral column morphology J:120066
absent intervertebral disk J:120066
decreased body weight J:120066
decreased bone mineral density J:120066
decreased compact bone thickness J:120066
decreased fibroblast cell migration J:120066
embryonic lethality during organogenesis, incomplete penetrance J:120066
kyphoscoliosis J:120066
perinatal lethality, incomplete penetrance J:120066
premature death J:120066
short tibia J:120066
vertebral fusion J:120066
FlnbGt(RRF239)Byg/FlnbGt(RRF239)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal radius morphology J:132026
abnormal sternum morphology J:132026
abnormal ulna morphology J:132026
decreased body size J:132026
decreased body weight J:132026
fused carpal bones J:132026
neonatal lethality, incomplete penetrance J:132026
postnatal lethality, incomplete penetrance J:132026
scoliosis J:132026
vertebral fusion J:132026
FlnbGt(XD076)Byg/FlnbGt(XD076)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal bone mineralization J:134094
abnormal bone ossification J:134094
abnormal chondrocyte morphology J:134094
abnormal posture J:134094
abnormal sternebra morphology J:134094
cervical vertebral fusion J:134094
decreased body size J:134094
decreased survivor rate J:134094
fused carpal bones J:134094
kyphosis J:134094
postnatal lethality, incomplete penetrance J:134094
Flnbskm2/Flnbskm2
involves: 129S1/SvImJ * 129X1/SvJ * DBA/2J 		abnormal gait J:218364
abnormal sternum morphology J:218364
abnormal thoracic cage morphology J:218364
decreased body height J:218364
decreased rib number J:218364
dehydration J:218364
lordosis J:218364
preweaning lethality, incomplete penetrance J:218364
scoliosis J:218364
tachypnea J:218364
thoracic vertebral fusion J:218364
Flnbtm1b(KOMP)Wtsi/Flnb+
C57BL/6N-Flnbtm1b(KOMP)Wtsi/H 		decreased bone mineral content J:211773
decreased bone mineral density J:211773
decreased lean body mass J:211773
decreased neutrophil cell number J:211773
decreased red blood cell distribution width J:211773
increased circulating serum albumin level J:211773
increased total body fat amount J:211773
Flnbtm1b(KOMP)Wtsi/Flnbtm1b(KOMP)Wtsi
C57BL/6N-Flnbtm1b(KOMP)Wtsi/H 		preweaning lethality, complete penetrance J:211773
Flnbtm1Vshn/Flnbtm1Vshn
involves: 129S6/SvEvTac * C57BL/6 		abnormal cell adhesion J:125095
abnormal chondrocyte morphology J:125095, J:213355
abnormal chondrocyte physiology J:125095, J:213355
abnormal extracellular matrix morphology J:125095
abnormal limb bone morphology J:125095
abnormal long bone epiphyseal plate morphology J:213355
abnormal long bone epiphyseal plate proliferative zone J:125095, J:213355
abnormal neurocranium morphology J:125095
abnormal occipital bone morphology J:125095
abnormal parietal bone morphology J:125095
abnormal patella morphology J:125095
abnormal perichondrium morphology J:125095
abnormal radius morphology J:125095
abnormal skeleton development J:125095
abnormal thoracic cage morphology J:125095
abnormal ulna morphology J:125095
abnormal viscerocranium morphology J:125095
brachyphalangia J:125095
cervical vertebral fusion J:125095
decreased bone mineral density J:125095
decreased bone mineral density of vertebrae J:125095
decreased bone mineralization J:125095
decreased bone ossification J:125095
decreased diameter of radius J:125095
decreased diameter of ulna J:125095
decreased distal limb length J:125095
decreased length of long bones J:213355
decreased long bone epiphyseal plate size J:125095, J:213355
decreased width of hypertrophic chondrocyte zone J:125095
delayed bone ossification J:125095
delayed endochondral bone ossification J:125095
delayed intramembranous bone ossification J:125095
increased width of hypertrophic chondrocyte zone J:213355
joint laxity J:125095
kyphosis J:125095
lordosis J:125095
postnatal growth retardation J:125095
preweaning lethality, incomplete penetrance J:125095
rib fusion J:125095
scoliosis J:125095
short radius J:125095, J:213355
slow postnatal weight gain J:125095
small thoracic cage J:125095
thin ribs J:125095
vertebral fusion J:125095
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory