Hace1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Hace1
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
MGI:2446110

5 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Hace1^{tm1b(KOMP)Wtsi}/Hace1^{tm1b(KOMP)Wtsi} C57BL/6N-Hace1^{tm1b(KOMP)Wtsi}/H	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Hace1^tm1Pngr/Hace1⁺ involves: 129P2/OlaHsd * C57BL/6	increased lung tumor incidence	J:125183
Hace1^tm1Pngr/Hace1^tm1Pngr involves: 129P2/OlaHsd * C57BL/6	increased lung tumor incidence	J:125183
	increased T cell derived lymphoma incidence	J:125183
	increased tumor incidence	J:125183

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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