Sidt2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sidt2
SID1 transmembrane family, member 2
MGI:2446134

32 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sidt2^{em1(IMPC)Wtsi}/Sidt2^{em1(IMPC)Wtsi} C57BL/6N-Sidt2^{em1(IMPC)Wtsi}/Wtsi	decreased circulating calcium level	J:211773
	decreased circulating cholesterol level	J:211773
	decreased circulating glycerol level	J:211773
	decreased circulating HDL cholesterol level	J:211773
	decreased circulating iron level	J:211773
	decreased circulating LDL cholesterol level	J:211773
	decreased circulating total protein level	J:211773
	increased circulating amylase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	thrombocytosis	J:211773
Sidt2^tm1.1Hzha/Sidt2^tm1.1Hzha involves: 129S6/SvEvTac * C57BL/6J	abnormal endoplasmic reticulum morphology	J:236042
	abnormal hepatocyte morphology	J:236042
	abnormal insulin secretion	J:204228
	abnormal liver morphology	J:236042
	abnormal pancreatic beta cell morphology	J:204228
	decreased body size	J:204228
	decreased body weight	J:204228
	decreased circulating insulin level	J:204228
	hepatic necrosis	J:236042
	hepatic steatosis	J:236042
	normal homeostasis/metabolism phenotype	J:204228
	impaired glucose tolerance	J:204228
	increased circulating alanine transaminase level	J:236042
	increased circulating aspartate transaminase level	J:236042
	increased circulating glucose level	J:204228
	increased circulating triglyceride level	J:236042
	increased endoplasmic reticulum stress	J:236042
	increased liver free fatty acids level	J:236042
	increased liver triglyceride level	J:236042
	increased pancreatic beta cell number	J:204228
	liver fibrosis	J:236042
	liver inflammation	J:236042
Sidt2^tm1Hzha/Sidt2^tm1Hzha involves: 129S6/SvEvTac * C57BL/6J	no abnormal phenotype detected	J:204228

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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