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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sidt2
SID1 transmembrane family, member 2
MGI:2446134
32 phenotypes from 3 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Sidt2em1(IMPC)Wtsi/Sidt2em1(IMPC)Wtsi
C57BL/6N-Sidt2em1(IMPC)Wtsi/Wtsi 		decreased circulating calcium level J:211773
decreased circulating cholesterol level J:211773
decreased circulating glycerol level J:211773
decreased circulating HDL cholesterol level J:211773
decreased circulating iron level J:211773
decreased circulating LDL cholesterol level J:211773
decreased circulating total protein level J:211773
increased circulating amylase level J:211773
increased circulating aspartate transaminase level J:211773
thrombocytosis J:211773
Sidt2tm1.1Hzha/Sidt2tm1.1Hzha
involves: 129S6/SvEvTac * C57BL/6J 		abnormal endoplasmic reticulum morphology J:236042
abnormal hepatocyte morphology J:236042
abnormal insulin secretion J:204228
abnormal liver morphology J:236042
abnormal pancreatic beta cell morphology J:204228
decreased body size J:204228
decreased body weight J:204228
decreased circulating insulin level J:204228
hepatic necrosis J:236042
hepatic steatosis J:236042
normal homeostasis/metabolism phenotype J:204228
impaired glucose tolerance J:204228
increased circulating alanine transaminase level J:236042
increased circulating aspartate transaminase level J:236042
increased circulating glucose level J:204228
increased circulating triglyceride level J:236042
increased endoplasmic reticulum stress J:236042
increased liver free fatty acids level J:236042
increased liver triglyceride level J:236042
increased pancreatic beta cell number J:204228
liver fibrosis J:236042
liver inflammation J:236042
Sidt2tm1Hzha/Sidt2tm1Hzha
involves: 129S6/SvEvTac * C57BL/6J 		no abnormal phenotype detected J:204228
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory