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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Eif2b5
eukaryotic translation initiation factor 2B, subunit 5 epsilon
MGI:2446176
19 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Eif2b4tm1.1Vdk/Eif2b4+
Eif2b5tm1.1Vdk/Eif2b5tm1.1Vdk
involves: C57BL/6 * C57BL/6J 		abnormal astrocyte morphology J:234659
abnormal axon morphology J:234659
abnormal cerebellum white matter morphology J:234659
abnormal myelination J:234659
abnormal retina morphology J:234659
ataxia J:234659
brain vacuoles J:234659
decreased body weight J:234659
premature death J:234659
sporadic seizures J:234659
Eif2b4tm1.1Vdk/Eif2b4tm1.1Vdk
Eif2b5tm1.1Vdk/Eif2b5+
involves: C57BL/6 * C57BL/6J 		abnormal astrocyte morphology J:234659
abnormal axon morphology J:234659
abnormal cerebellum white matter morphology J:234659
abnormal myelination J:234659
abnormal retina morphology J:234659
ataxia J:234659
brain vacuoles J:234659
decreased body weight J:234659
premature death J:234659
sporadic seizures J:234659
Eif2b4tm1.1Vdk/Eif2b4tm1.1Vdk
Eif2b5tm1.1Vdk/Eif2b5tm1.1Vdk
involves: C57BL/6 * C57BL/6J 		abnormal cerebellum white matter morphology J:234659
abnormal forebrain morphology J:234659
abnormal myelination J:234659
abnormal retina inner nuclear layer morphology J:234659
abnormal retina morphology J:234659
abnormal retina outer nuclear layer morphology J:234659
ataxia J:234659
brain vacuoles J:234659
decreased body weight J:234659
decreased oligodendrocyte number J:234659
ectopic Bergmann glia cells J:234659
increased hyaluronic acid level J:234659
increased oligodendrocyte progenitor number J:234659
lethality at weaning J:234659
sporadic seizures J:234659
thin retina inner plexiform layer J:234659
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory