Cpt1c Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cpt1c
carnitine palmitoyltransferase 1c
MGI:2446526

20 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cpt1c^{tm1b(EUCOMM)Wtsi}/Cpt1c^{tm1b(EUCOMM)Wtsi} C57BL/6N-Cpt1c^{tm1b(EUCOMM)Wtsi}/Ucd	abnormal uterus morphology	J:211773
	decreased bone mineral content	J:211773
	decreased brain weight	J:211773
	increased total body fat amount	J:211773
Cpt1c^tm1Dhwu/Cpt1c^tm1Dhwu involves: 129 * C57BL/6J	decreased skeletal muscle cell glucose uptake	J:148205
	enhanced gluconeogenesis	J:148205
	normal growth/size/body region phenotype	J:148205
	increased circulating glucose level	J:148205
	increased circulating insulin level	J:148205
	increased liver triglyceride level	J:148205
	insulin resistance	J:148205
Cpt1c^tm1Fghe/Cpt1c^tm1Fghe B6.129S-Cpt1c^tm1Fghe	abnormal dendritic spine morphology	J:186508
	abnormal lipid level	J:186508
	abnormal spatial learning	J:186508
Cpt1c^tm1Mdln/Cpt1c^tm1Mdln involves: C57BL/6	decreased body weight	J:109455
	decreased food intake	J:109455
	hepatic steatosis	J:109455
	hyperlipidemia	J:109455
	increased circulating triglyceride level	J:109455
	increased susceptibility to weight gain	J:109455
	insulin resistance	J:109455

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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